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Filtered Search Results
ABclonal Technology LEF1 Rabbit pAb
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This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
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Gold Biotechnology Inc BLUEstain™ 2 Protein ladder, 5-245 kDa 500 µL
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The BLUEstainTM 2 Protein ladder is a three-color protein standard with 13 prestained proteins, covering a wide range molecular weights from 3.5 to 245 kDa. Proteins are covalently coupled with a blue chromophore except for two reference bands (one green and one red band at 25 kDa and 75 kDa respectively) when separated on SDS-PAGE (Tris-glycine buffer).
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ABclonal Technology CACNG1 Rabbit pAb
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Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs).
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ABclonal Technology RAIDD/CRADD Rabbit mAb
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This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
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S2 Media 15x100mm Chameleon™ COLOREX™ ESBL (RUO), 10/pack
Chameleon™ COLOREX™ ESBL (RUO) is a selective and differential, chromogenic culture medium used for the qualitative direct detection of gastrointestinal colonization with Extended-Spectrum-Beta-Lactamase (ESBL) resistant Enterobacteria. Test specimens include rectal swabs and stools. For Research Use Only (RUO). Not for use in diagnostic procedures unless Laboratory Developed Test (LDT) validation with the product has been completed. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ ESBL should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
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ABclonal Technology IGF1 Rabbit pAb
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The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
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ABclonal Technology SOD1 Rabbit pAb
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The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
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ABclonal Technology FCHSD1 Rabbit pAb
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Predicted to enable lipid binding activity. Predicted to be involved in neuromuscular synaptic transmission and positive regulation of actin filament polymerization. Predicted to be located in cell projection and perikaryon. Predicted to be active in neuromuscular junction and recycling endosome. Predicted to colocalize with cuticular plate.
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ABclonal Technology eEF1A1 Rabbit pAb
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This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.
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ABclonal Technology PCF11 Rabbit pAb
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The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3 product of polyA site cleavage.
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Cayman Chemical PI-103hydrochlorIde 10mg
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A potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50 = 2, 8, 20, 26, 48, 83, 88, and 150 nM for DNA-PK, p110α, mTORC1, PI3-KC2β, p110δ, mTORC2, p110β, and p110γ, respectively)
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ABclonal Technology RBP7 Rabbit pAb
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The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs, however, it has a lower binding affinity for retinol than other CRBPs.
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S2 Media 15x100mm Chameleon™ COLOREX™ Campylobacter, 10/pack
Chameleon™ COLOREX™ Campylobacter is a selective and differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of thermotolerant Campylobacter. Test specimens include rectal swabs and stools. Chameleon™ COLOREX™ Campylobacter can also be used in the detection of Campylobacter in the analyses of food products for human consumption, animal feed, and in environmental samples in accordance with the ISO 10272-1. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies.• Product meets CLSI and ISO performance criteria.• Chameleon™ COLOREX™ Campylobacter should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
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ABclonal Technology DICER1 Rabbit pAb
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This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. This protein also acts as a strong antiviral agent with activity against RNA viruses, including the Zika and SARS-CoV-2 viruses. Alternative splicing results in multiple transcript variants.
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STEMCELL Technologies EasySepTM Human CD4 Positive
Large-scale immunomagnetic positive selection of human CD4plus cells (e.g. CD4plus T cells) - 1 x 10.10 cells
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